Important updates to the 2007/2008 cycle

Research priorities

• Discovery or development of new recombinant molecules with potential therapeutic value in bleeding disorders
• New delivery options for these molecules, including gene delivery
• Surveys and/or clinical studies focusing on treatment modalities for hemophilia, i.e., prophylaxis
• Research to define a basis for inhibitor development in hemophilia
• Clinical studies focusing on the treatment of adverse events associated with hemophilia, e.g., inhibitor development
• Health outcomes and quality of life research related to hemophilia

Previous research

Over the previous five award cycles, the program has provided funding to support several projects in the following areas:

• Aspects of the molecular biology of vWF structure and function, and the diagnosis and treatment of vWD
• The function and regulation of platelets and the diagnosis of platelet disorders

As a result, the program will not award projects in these areas during this award cycle.

Eligibility criteria

Uninterrupted funding and multiple awards
Applicants may only receive one Clinical Training Award and one Early Career Award from the program. Applicants who have received funding for a Special Projects Award must wait 1 year from the expiration of current funding before reapplying to this category.

Multiple applications from the same institution
More than one application from the same institution, i.e., university, hospital or hemophilia center, is permitted. However, multiple applications from the same group of researchers at such an institute, i.e., those working in the same laboratory or department, are not permitted.

Translational research
For applications to the Early Career and Special Project categories, applicants will be required to describe how their proposed research will translate into clinical benefits for patients with hemophilia and to those healthcare professionals providing care. The applications that offer the most compelling translational opportunities will be given greater weight during the review process.

Clinical Training Award

The Clinical Training Award (formerly Clinical Scholarship Award) is intended to facilitate the development of specific clinical expertise in the field of hemophilia for applicants who have completed medical training and have an interest in pursuing a career as a hemophilia clinician.